| 1. | As a family, these residues are known as sialic acids.
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| 2. | In bacterial systems, sialic acids are biosynthesized by an aldolase enzyme.
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| 3. | These enzymes can be used for chemoenzymatic synthesis of sialic acid derivatives.
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| 4. | Neural membranes have 20 times more sialic acid than other cellular membranes.
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| 5. | The most common form is tetrasialotransferrin, with four sialic acid chains.
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| 6. | Also, alpha-amylase contains a significant level of sialic acid.
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| 7. | ISSD is the most severe form of the sialic acid storage diseases.
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| 8. | Neuraminidases cleave the terminal sialic acid residues from carbohydrate chains in glycoproteins.
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| 9. | This suggests that sialic acid has an influence upon brain development and learning.
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| 10. | Cellular receptors for polyomaviruses are sialic acid residues of glycans, commonly gangliosides.
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